- Vitamin B12 malabsorption (in the long run lack of Vit B12 can contribute to megaloblastic anemia)
- hair loss (which is also one of the symptoms of PCOS)
- lactic acidosis - the most serious side effect but this is also rare
- loss of appetite (hmmm...I wish I had this one so that I can lose more weight as I'm defintely overweight)
- GI disturbance(vomiting, nausea and diarrhea falls in this category)
- malaise, fatigue and achiness
Thursday, October 8, 2009
Sunday, August 23, 2009
According to Natural Health Solutions for PCOS metformin works in 3 ways.
- Metformin decreases the absorption of dietary carbohydrates through the intestines.
- It reduces the production of glucose by the liver. The liver uses the raw material in your food to create a reserve supply of blood sugar. When your body experiences stress, the liver releases the reserve glucose to supply your brain and muscles with an immediate source of energy to cope with the stress. Metformin suppresses the production of this reserve fuel.
- Perhaps most importantly, metformin increases the sensitivity of muscle cells to insulin. Insulin is the hormone that delivers glucose into your cells to be burned as fuel, or stored. Women with PCOS frequently have "insulin resistance", a condition where excessive amounts of insulin are required in order to get blood glucose moved into cells, where it belongs. Metformin helps your body to transport glucose with relatively less insulin, thus lowering your insulin levels. Chronically high levels of either glucose or insulin in your blood contributes to obesity, heart disease, infertility, and certain cancers, as well as the development of diabetes.
When I was prescribed with Metformin I had to start with 500mg for a week. Then on the second week the dosage was doubled. And finally on the third week I was instructed to drink 1500mg of Metformin. This is the dosage that I have been drinking for the past years. Eversince I started my Metformin intake my period has become regular. Although like most drugs Metformin also have its risks and side-effects which I will be talking about in another post.
Among my immediate family I am the only with PCOS. Although both my sisters have irregular menstruation too. The eldest is married and was able to bear child. The youngest is still single and dreads going to the OB to have herself checked.